Cognitive function tests are preformed using rodents and primates to assess the potential for cognitive improvement/impairment.
Compounds can be given by a number of routes including: IP, SC, Oral, ICV.
Deliverables from these studies include:
- Delayed Alternation Test of Working Memory
- Change in Accuracy from Baseline (performance measure)
- Change in Trial Duration from Baseline (motivational measure)
- Visual Signal Detection Test of Sustained Attention
- Change in Proportion of Correct Trials from Baseline
- Change in Probability of Correct Detection from Baseline (accuracy measure)
- Change in Probability of False Alarms from Baseline (impulsivity measure)
- Change in d' from Baseline (stimulus detectability measure)
- Conditioned Place Preference
(Degree to which a compound is reinforcing or aversive)
- Change From Baseline in Time Spent in an Environment Paired With a Compound
- Custom Behavioral Screens Available Upon Request
